Identifying potential therapeutic targets in non-melanoma skin cancer - a devastating complication of the genetic skin disease dystrophic epidermolysis bullosa (DEB) Dr Andrew South, Division of Surgery & Oncology, School of Medicine Certain genetic skin diseases predispose to developing non melanoma skin cancer. Recessive dystrophic epidermolysis bullosa (RDEB) is a devastating genetic skin disease characterised by chronic erosions and blistering of the skin. Not only do patients suffer from continual trauma induced skin fragility, but are at a huge increased risk of developing Squamous cell carcinoma (SCC). Unlike spontaneously arising SCC in the general population, RDEB SCC are highly aggressive and prone to metastasis, with 55% of all patients dying before the age of 40 years from this complication. A three-year PhD studentship funded by DEBRA is available immediately to join Dr Andrew South and the EB team at Dundee University, who have been working towards genetic characteris...