Reference: MRTN_CT_2006_035946 Summary: Looking for a candidate with background in one or more of biophysics, molecular and cell biology, immunology, microscopic imaging to investigate molecular interactions between MHC class I and II molecules and TCR receptor in immune synapse formation. Description A Postdoctoral fellowship (2 years) is available within the framework of a Marie Curie Research Training Network (Immunanomap, MRTN_CT_2006_035946). Research objectives: The topology, conformation and lateral mobility of the membrane proteins during this process play an important role in these processes. We would also like to investigate the changes of the cell surface distribution of MHC class I and II molecules. We aim to discover connections between the immunological function of MHC molecules and their supercluster formation on cells with modified expression levels by studying the rotational and lateral mobility of these receptor complexes using the available up-to-date spectroscopi...